The four-member cast comprises Drama Desk nominee Farah Alvin (The Marvelous Wonderettes), Natalie Venetia Belcon (Avenue Q), John Bolton (A Christmas Story, "Gossip Girl") and Jake Boyd (MCC's Carrie).

The musical features book and lyrics by Tony Award nominee Bill Russell (Side Show) and music by Drama Desk nominee Peter Melnick (Adrift in Macao). Tony Award-winning producer Andy Sandberg (Hair; Gore Vidal’s The Best Man) directs the production with choreography by AC Ciulla (Footloose).

"In a world where smoking has recently been outlawed and the penalties are growing stricter by the minute, Pam is having an impossible time trying to quit," according to press notes. "Her husband Ernie dreams of being a rock star and relentlessly practices his guitar in the basement, while their videogame-addicted son Jimmy listens to so much rap music he thinks he's black. As if Pam isn't pushed to the edge of reason already, her nosy, anti-smoking zealot neighbor Phyllis is on a mission to catch transgressors mid-puff. Will Pam kick the habit or fight for her right to light up?"

Here's a look at opening night:

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Last Smoker in America, With Farah Alvin and John Bolton, Opens Off-Broadway

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For more information, please visit lastsmoker.com.