Mosher, who starred in Hairspray on Broadway, succeeds Leslie Kritzer. Nightlife performer McNamara is stepping in for a limited run, filling in for Christine Pedi until Oct. 26.

"I've been waiting years to work with both of these comedic geniuses," producer Tom D'Angora said in a recent statement. "The timing couldn't be more perfect and we are blessed to have them on our team."

The show also features Michael West, Tommy Walker, Amy Griffin and Ryan Knowles.

NEWSical the Musical, penned by Rick Crom, is the "ever-evolving, completely un-sanitized musical mockery of all the news that's fit to spoof. From John Travolta, Anderson Cooper, Tom Cruise and Katie Holmes to the national fight for marriage equality and the 2012 Presidential Election, NEWSical the Musical sets all of today's biggest news and pop culture headlines to song." Mark Waldrop directs.

Rounding out the creative team are Ed Goldschneider (music director), Jason Courson (set designer), Josh Starr (lighting designer) and Scott Delacruz (stage manager).

Newsical the Musical is produced by Tom D'Angora.

NEWSical the Musical plays at Theatre Row (410 West 42nd Street). Tickets are $85-$110 and can be purchased through Telecharge.com or by calling (212) 279-4200 or (800) 432-7250. For performance schedule and more information, visit NEWSicalthemusical.com.